Annals of Rheumatology and Autoimmunity

CASE REPORT
Year
: 2022  |  Volume : 2  |  Issue : 1  |  Page : 6--9

Necrotizing Myopathy with Abundant Macrophages in Childhood Systemic Lupus Erythematosus


Aisha Mirza1, Sharifa Alyaeesh1, Amal Albalawi1, Khalid Alismail2, Hindi Al-Hindi3, Abdullah Alsonbul1, Sulaiman M Al-Mayouf4 
1 Pediatric Rheumatology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
2 Musculoskeletal Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
3 Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
4 Pediatric Rheumatology, King Faisal Specialist Hospital and Research Center; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

Correspondence Address:
Dr. Sulaiman M Al-Mayouf
Department of Pediatrics, King Faisal Specialist Hospital and Research Center, College of Medicine, Alfaisal University, Po Box 3354, Riyadh 11211
Saudi Arabia

Childhood systemic lupus erythematosus (cSLE) is a heterogeneous complex multisystem disease with substantial complications. We report a girl with refractory SLE developed myalgia and muscle weakness involving proximal and distal lower extremities as a sequel of macrophage activation syndrome. Muscle biopsy and proper staining revealed a rare necrotizing myopathy with interstitial macrophages which expands the differential diagnosis of inflammatory muscle disease in cSLE.


How to cite this article:
Mirza A, Alyaeesh S, Albalawi A, Alismail K, Al-Hindi H, Alsonbul A, Al-Mayouf SM. Necrotizing Myopathy with Abundant Macrophages in Childhood Systemic Lupus Erythematosus.Ann Rheumatol Autoimmun 2022;2:6-9


How to cite this URL:
Mirza A, Alyaeesh S, Albalawi A, Alismail K, Al-Hindi H, Alsonbul A, Al-Mayouf SM. Necrotizing Myopathy with Abundant Macrophages in Childhood Systemic Lupus Erythematosus. Ann Rheumatol Autoimmun [serial online] 2022 [cited 2022 Aug 19 ];2:6-9
Available from: http://www.ara.ssr.com/article.asp?issn=WKMP-0240;year=2022;volume=2;issue=1;spage=6;epage=9;aulast=Mirza;type=0