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   Table of Contents - Current issue
January-April 2022
Volume 2 | Issue 1
Page Nos. 1-33

Online since Wednesday, May 25, 2022

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Demographic similarity and variability between patients with juvenile idiopathic arthritis in the gulf cooperation council countries p. 1
Fatimah AlKhars, Nora Almutairi, Sulaiman M Al-Mayouf
To highlight the similarities and variability between patients with juvenile idiopathic arthritis (JIA) in the Gulf Cooperation Council (GCC) countries. We comprehensively conducted electronic searches through PubMed and Google Scholar for relevant studies using the appropriate MeSH terms related to demographic and clinical features of JIA. The search was limited to articles from January 1988 to October 2021. Authors independently reviewed the searched literature to identify eligible studies. Citations from selected articles were also checked for additional eligible studies. Data were retrieved from seven eligible studies. A total of 757 JIA patients with a mean age of 10.7 ± 4.6 years were identified from four different countries (Saudi Arabia, UAE, Kuwait, and Oman); there were no published reports from Bahrain or Qatar. Two studies identified the estimated prevalence rate of nearly 20 per 100,000. There was a female predominance (62.1%). The mean age at the onset of JIA manifestations was 6.3 ± 3.9 years. Thirty-two out of 377 (8.5%) patients had a positive family history of JIA. Interestingly, Omani cohort had the highest frequency (9.8%) of affected siblings with JIA. The most frequent JIA subtypes were oligoarticular JIA, followed by polyarticular and systemic JIA. Of note, oligoarticular JIA was more frequent in UAE and Omani cohorts, while systemic JIA was more prevalent in Saudi and Kuwaiti cohorts. Uveitis occurred in 5.0% (n = 38) of patients during their disease course, mostly in oligoarticular category. Detection of positive anti-nuclear antibody was in 37.3% while rheumatoid factor and anti-cyclic citrullinated peptide were 21% and 10.5% respectively. Our findings estimated the number of children affected by JIA, and showed demographic similarities between patients. However, more studies are needed to address the incidence and prevalence, and the true burden of this disease in the GCC countries.
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Necrotizing Myopathy with Abundant Macrophages in Childhood Systemic Lupus Erythematosus p. 6
Aisha Mirza, Sharifa Alyaeesh, Amal Albalawi, Khalid Alismail, Hindi Al-Hindi, Abdullah Alsonbul, Sulaiman M Al-Mayouf
Childhood systemic lupus erythematosus (cSLE) is a heterogeneous complex multisystem disease with substantial complications. We report a girl with refractory SLE developed myalgia and muscle weakness involving proximal and distal lower extremities as a sequel of macrophage activation syndrome. Muscle biopsy and proper staining revealed a rare necrotizing myopathy with interstitial macrophages which expands the differential diagnosis of inflammatory muscle disease in cSLE.
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Coexistence of ankylosing spondylitis and seropositive rheumatoid arthritis p. 10
Fatemah Abbas Aldahneen, Abdulrahim Samir Almotairy, Hanan Ali Alhamzi
Although rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are among the most common rheumatic diseases, reports of patients who had a combination of both diseases are rare. There are no one classification criteria to diagnose the coexistence of both. This coexistence is a rare presentation that has an implication on the patient management. We are presenting the case of a 69-year-old male who had an unusual combination of AS and RA manifestations and we reviewed similar cases that previously reported to see what the features of those cases are and how can this combination affect the patient management.
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Novel diagnosis of systemic lupus erythematosus after first dose of COVID-19 vaccination p. 14
Khalid S Alshahrani, Jorge Sanchez-Guerrero
In the literature, there are two case reports of new diagnoses of systemic lupus erythematosus including a patient with early-onset of class V nephritis; both cases had received the AstraZeneca Vaccine. There are also several cases-reports of autoimmune disease flares after receiving the first or the second dose of the different COVID-19 vaccinations. The severity of the disease flares, the number of doses after which the disease flared, and the approach to control the flare manifestations vary across the reports. The majority of the case reports focus on disease activation rather than a newly diagnosed autoimmune disease after receiving the COVID-19 vaccines. Here, we report a young female with new-onset systemic lupus erythematosus manifesting with arthritis, cutaneous manifestations, and fever 5 days after the first dose of (ChAdOx1 nCoV-19) vaccine.
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The 8th Annual Saudi Society for Rheumatology Conference: The Abstracts Young Investigator p. 17

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The 8th Annual Saudi society for rheumatology conference: The abstracts oral p. 22

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Posters for the 8th Annual Saudi Society for rheumatology conference p. 27

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