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CASE REPORT
Year : 2022  |  Volume : 2  |  Issue : 1  |  Page : 6-9

Necrotizing Myopathy with Abundant Macrophages in Childhood Systemic Lupus Erythematosus


1 Pediatric Rheumatology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
2 Musculoskeletal Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
3 Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
4 Pediatric Rheumatology, King Faisal Specialist Hospital and Research Center; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

Correspondence Address:
Dr. Sulaiman M Al-Mayouf
Department of Pediatrics, King Faisal Specialist Hospital and Research Center, College of Medicine, Alfaisal University, Po Box 3354, Riyadh 11211
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ara.ara_6_21

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Childhood systemic lupus erythematosus (cSLE) is a heterogeneous complex multisystem disease with substantial complications. We report a girl with refractory SLE developed myalgia and muscle weakness involving proximal and distal lower extremities as a sequel of macrophage activation syndrome. Muscle biopsy and proper staining revealed a rare necrotizing myopathy with interstitial macrophages which expands the differential diagnosis of inflammatory muscle disease in cSLE.


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