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Year : 2022  |  Volume : 2  |  Issue : 1  |  Page : 14-16

Novel diagnosis of systemic lupus erythematosus after first dose of COVID-19 vaccination

Division of Rheumatology, Sinai Health System/University Health Network, University of Toronto, Ontario, Canada

Correspondence Address:
Dr. Jorge Sanchez-Guerrero
60 Murray St. 2-005. Toronto, ON, M5T 3L9
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ara.ara_10_21

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In the literature, there are two case reports of new diagnoses of systemic lupus erythematosus including a patient with early-onset of class V nephritis; both cases had received the AstraZeneca Vaccine. There are also several cases-reports of autoimmune disease flares after receiving the first or the second dose of the different COVID-19 vaccinations. The severity of the disease flares, the number of doses after which the disease flared, and the approach to control the flare manifestations vary across the reports. The majority of the case reports focus on disease activation rather than a newly diagnosed autoimmune disease after receiving the COVID-19 vaccines. Here, we report a young female with new-onset systemic lupus erythematosus manifesting with arthritis, cutaneous manifestations, and fever 5 days after the first dose of (ChAdOx1 nCoV-19) vaccine.

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